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• Viscous gel composed of hydrogel nanoparticles suspended in water with biocompatible chemical composition.
• Physical properties can be controlled by changing formulation variables.
  • Particle size
  • Crosslink density
  • Monomers and comonomers incorporated into formulation
• Physical characteristics
  • Elasticity can be modified to change the rate of modulus with stress.
  • Modulus can be modified to mimic specific adipose tissue.
• Gel aggregates on contact with normal serum with no migration into lymphatic tissue.
• Potential to seal slow leak at site with no further material release.

• Increasing polymer weight percent in gel increases resistance to deflection.
• Increasing HPMA percent composition increases resistance to deflection.
• Deflection is nonlinear but this is consistent with elastic gel materials