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Transmucosal Drug
Delivery (OraDisc™) |
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Formulation
Flexibility: |
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The mucoadhesive
film can be designed to erode over a period of time ranging
from 15 minutes to 3 hours. This is achieved by: |
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- Adjusting
the ratio of hydrophobic polymers to hydrophilic polymers
-within a range of 1:1 to 8:1.
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Adjusting the
thickness of the controlled erosion layer.
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Adjusting the
thickness of the mucoadhesive layer.
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Active substance
can be incorporated in all layers of the device: |
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Active is
incorporated in the mucoadhesive layer for systemic delivery
or local delivery to the mucosal surface.
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Active is
incorporated in the controlled erosion layer or outer layers
for multiple release profiles to the oral cavity.
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The size and shape
of the mucoadhesive film device can be altered depending on
the application and the amount of drug to be delivered. |
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The mucoadhesive
film has also been designed to adhere and deliver actives to
the tooth surface. |
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