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Transmucosal Drug
Delivery (OraDisc™) |
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Product
Opportunities-Prescription: |
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Opportunity for
administration of products which currently cannot be
effectively delivered orally: |
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- Poor GI
tract absorption.
- Degradation
by enzymes or low pH environment.
- Extensive
first-pass metabolism.
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Delayed onset of
action due to delayed absorption.
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Product
opportunities identified for development: |
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- Pain
management (e.g. cancer pain, post surgical pain)
- Emesis
(chemotherapy induced, post surgical emesis)
- Migraine
- Radiation
induced oral thrush
- Enhancing
weight gain (e.g. cancer and AIDS patients)
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Product
Opportunities-Consumer (OTC): |
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The mucoadhesive
film technology is designed to overcome the problems
associated with delivering products to the oral mucosa: |
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- Saliva can
rapidly wash away a topically applied active compound prior
to the therapeutic benefit being achieved.
- Action of
eating, speaking, and drinking is some of the problems that
have limited the usefulness of adherent pharmaceutical
carriers.
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Opportunities for
delivery to the oral cavity include: |
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- Cough
suppressant
- Sore throat
remedy
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Antimicrobials
- Breath
freshener
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Opportunities for
delivery to the tooth surface include: |
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- Tooth
whitening erodible strip
-
De-sensitizing strip
- Fluoride
strip
- Enhance
tooth enamel strip
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